Study
Novel Epigenetic Markers for Toxicity after Intraoperative and Conventional Radiotherapy for Breast Cancer
Study ID | Alternative Stable ID | Type |
---|---|---|
EGAS00001001279 | Other |
Study Description
Ionizing radiation is a common treatment option for cancer but its use is limited by the unpredictable and highly heterogeneous onset of late side effects, especially radiation-induced fibrosis. Clinically applicable biomarkers and effective treatments for radiation fibrosis are currently unavailable. In order to identify novel markers we ran a genome-wide DNA methylation screen in primary dermal fibroblasts obtained from breast cancer patients before intraoperative radiotherapy. Cells from patients developing fibrosis within a three-year follow up were compared to those without fibrosis (12 individuals per group). Illumina Infinium HumanMethylation450 BeadChip Technology was used.
Study Datasets 2 datasets.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
---|---|---|---|
EGAD00010001879 |
Control human dermal fibroblasts from patient forearm
|
Illumina 450k | 12 |
EGAD00010001880 |
Case human dermal fibroblasts from patient forearm
|
Illumina 450k | 12 |
Who archives the data?

Publications
Citations
Retrieving...

Retrieving...
