Multiregion Whole Exome sequencing of paediatric High Grade Gliomas and DIPG
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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The failure to develop effective therapies for paediatric glioblastoma (pGBM) and diffuse intrinsic pontine glioma (DIPG) is in part due to their intrinsic heterogeneity. Analysis of 142 sequenced cases revealed multiple tumour subclones, spatially and temporally co-existing in a stable manner as observed by multiple sampling strategies. This dataset provides multi region sequencing of high grade gliomas and diffuse intrinsic pontine gliomas from 15 patients. DNA was extracted from FFPE ... (Show More)
|Illumina HiSeq 2000||79|