BLUEPRINT EpiVar 450K DNA methylation profiles of naive CD4+ T-cells, monocytes & neutrophils

Dataset ID	Description	Technology	Samples
EGAD00010000850	BLUEPRINT DNA methylation profiles of monocytes, neutrophils and T cells from healthy donors		525

Publications	Citations
Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells. Chen L, Ge B, Casale FP, Vasquez L, Kwan T, Garrido-Martín D, Watt S, Yan Y, Kundu K, Ecker S, Datta A, Richardson D, Burden F, Mead D, Mann AL, Fernandez JM, Rowlston S, Wilder SP, Farrow S, Shao X, Lambourne JJ, Redensek A, Albers CA, Amstislavskiy V, Ashford S, Berentsen K, Bomba L, Bourque G, Bujold D, Busche S, Caron M, Chen SH, Cheung W, Delaneau O, Dermitzakis ET, Elding H, Colgiu I, Bagger FO, Flicek P, Habibi E, Iotchkova V, Janssen-Megens E, Kim B, Lehrach H, Lowy E, Mandoli A, Matarese F, Maurano MT, Morris JA, Pancaldi V, Pourfarzad F, Rehnstrom K, Rendon A, Risch T, Sharifi N, Simon MM, Sultan M, Valencia A, Walter K, Wang SY, Frontini M, Antonarakis SE, Clarke L, Yaspo ML, Beck S, Guigo R, Rico D, Martens JHA, Ouwehand WH, Kuijpers TW, Paul DS, Stunnenberg HG, Stegle O, Downes K, Pastinen T, Soranzo N. Cell 167: 2016 1398-1414.e24	509
Increased DNA methylation variability in type 1 diabetes across three immune effector cell types. Paul DS, Teschendorff AE, Dang MA, Lowe R, Hawa MI, Ecker S, Beyan H, Cunningham S, Fouts AR, Ramelius A, Burden F, Farrow S, Rowlston S, Rehnstrom K, Frontini M, Downes K, Busche S, Cheung WA, Ge B, Simon MM, Bujold D, Kwan T, Bourque G, Datta A, Lowy E, Clarke L, Flicek P, Libertini E, Heath S, Gut M, Gut IG, Ouwehand WH, Pastinen T, Soranzo N, Hofer SE, Karges B, Meissner T, Boehm BO, Cilio C, Elding Larsson H, Lernmark Å, Steck AK, Rakyan VK, Beck S, Leslie RD. Nat Commun 7: 2016 13555	118
Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types. Ecker S, Chen L, Pancaldi V, Bagger FO, Fernández JM, Carrillo de Santa Pau E, Juan D, Mann AL, Watt S, Casale FP, Sidiropoulos N, Rapin N, Merkel A, BLUEPRINT Consortium, Stunnenberg HG, Stegle O, Frontini M, Downes K, Pastinen T, Kuijpers TW, Rico D, Valencia A, Beck S, Soranzo N, Paul DS. Genome Biol 18: 2017 18	88
Cell and tissue type independent age-associated DNA methylation changes are not rare but common. Zhu T, Zheng SC, Paul DS, Horvath S, Teschendorff AE. Aging (Albany NY) 10: 2018 3541-3557	44
A comparison of epigenetic mitotic-like clocks for cancer risk prediction. Teschendorff AE. Genome Med 12: 2020 56	104
Genetic variation in cis-regulatory domains suggests cell type-specific regulatory mechanisms in immunity. Avalos D, Rey G, Ribeiro DM, Ramisch A, Dermitzakis ET, Delaneau O. Commun Biol 6: 2023 335	10
Quantifying the stochastic component of epigenetic aging. Tong H, Dwaraka VB, Chen Q, Luo Q, Lasky-Su JA, Smith R, Teschendorff AE. Nat Aging 4: 2024 886-901	41
Cell-type-specific subtyping of epigenomes improves prognostic stratification of cancer. Luo Q, Teschendorff AE. Genome Med 17: 2025 34	0
Unified high-resolution immune cell fraction estimation in blood tissue from birth to old age. Guo X, Sulaiman M, Neumann A, Zheng SC, Cecil CAM, Teschendorff AE, Heijmans BT. Genome Med 17: 2025 63	3