S_CORT_Stratification_in_COloRecTal_cancer_

Colorectal cancer samples will be submitted for Illumina sequencing using a custom capture of 116 genes implicated in colorectal tumourigenesis. Driver mutations will be detected and ultimately correlated with phenotypic data.

Type: Cancer Genomics
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 2 Publications

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001009760	Colorectal cancer samples will be submitted for Illumina sequencing using a custom capture of 116 genes implicated in colorectal tumourigenesis. Driver mutations will be detected and ultimately correlated with phenotypic data.	Illumina HiSeq 2000 Illumina HiSeq 2500	2229

Publications	Citations
Tumour purity assessment with deep learning in colorectal cancer and impact on molecular analysis. Schoenpflug LA, Chatzipli A, Sirinukunwattana K, Richman S, Blake A, Robineau J, Mertz KD, Verrill C, Leedham SJ, Hardy C, Whalley C, Redmond K, Dunne P, Walker S, Beggs AD, McDermott U, Murray GI, Samuel LM, Seymour M, Tomlinson I, Quirke P, S:CORT consortium, Rittscher J, Maughan T, Domingo E, Koelzer VH. J Pathol 265: 2025 184-197	0
Analysis of IDH1 and IDH2 mutations as causes of the hypermethylator phenotype in colorectal cancer. Ward JC, Morgan M, Wood J, Woolley C, de Menezes AAN, Finch A, Sherwood K, Huang Q, Henry CS, Fernández-Tajes J, Soriano I, Thorn S, Legge I, McCullagh J, Kerr D, Kerr R, Hejmadi RK, Arends MJ, S:CORT Consortium, Domingo E, Maughan T, Bardella C, Tomlinson I. J Pathol 267: 2025 40-55	0

Publications

Citations

Tumour purity assessment with deep learning in colorectal cancer and impact on molecular analysis.
Schoenpflug LA, Chatzipli A, Sirinukunwattana K, Richman S, Blake A, Robineau J, Mertz KD, Verrill C, Leedham SJ, Hardy C, Whalley C, Redmond K, Dunne P, Walker S, Beggs AD, McDermott U, Murray GI, Samuel LM, Seymour M, Tomlinson I, Quirke P, S:CORT consortium, Rittscher J, Maughan T, Domingo E, Koelzer VH. J Pathol 265: 2025 184-197

Analysis of IDH1 and IDH2 mutations as causes of the hypermethylator phenotype in colorectal cancer.
Ward JC, Morgan M, Wood J, Woolley C, de Menezes AAN, Finch A, Sherwood K, Huang Q, Henry CS, Fernández-Tajes J, Soriano I, Thorn S, Legge I, McCullagh J, Kerr D, Kerr R, Hejmadi RK, Arends MJ, S:CORT Consortium, Domingo E, Maughan T, Bardella C, Tomlinson I. J Pathol 267: 2025 40-55