Low_depth_whole_genome_sequencing_across_multiple_isolated_populations

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Dataset ID	Description	Technology	Samples
EGAD00001002014	Isolated populations have unique population genetics characteristics that can help boost power in genetic association studies for complex traits. Leveraging these advantageous characteristics requires an in-depth understanding of parameters that have shaped sequence variation in isolates. This study performs a comprehensive investigation of these parameters using low-depth whole genome sequencing (WGS) across multiple isolates.		6840

Publications	Citations
Enrichment of low-frequency functional variants revealed by whole-genome sequencing of multiple isolated European populations. Xue Y, Mezzavilla M, Haber M, McCarthy S, Chen Y, Narasimhan V, Gilly A, Ayub Q, Colonna V, Southam L, Finan C, Massaia A, Chheda H, Palta P, Ritchie G, Asimit J, Dedoussis G, Gasparini P, Palotie A, Ripatti S, Soranzo N, Toniolo D, Wilson JF, Durbin R, Tyler-Smith C, Zeggini E. Nat Commun 8: 2017 15927	37
Whole-genome sequencing reveals new insights into age-related hearing loss: cumulative effects, pleiotropy and the role of selection. Vuckovic D, Mezzavilla M, Cocca M, Morgan A, Brumat M, Catamo E, Concas MP, Biino G, Franzè A, Ambrosetti U, Pirastu M, Gasparini P, Girotto G. Eur J Hum Genet 26: 2018 1167-1179	16
Hearing Function: Identification of New Candidate Genes Further Explaining the Complexity of This Sensory Ability. Concas MP, Morgan A, Serra F, Nagtegaal AP, Oosterloo BC, Seshadri S, Heard-Costa N, Van Camp G, Fransen E, Francescatto M, Logroscino G, Sardone R, Quaranta N, Gasparini P, Girotto G. Genes (Basel) 12: 2021 1228	1
Genetic Dissection of Temperament Personality Traits in Italian Isolates. Concas MP, Minelli A, Aere S, Morgan A, Tesolin P, Gasparini P, Gennarelli M, Girotto G. Genes (Basel) 13: 2021 4	2
Regulator of G-Protein Signalling 9: A New Candidate Gene for Sweet Food Liking? Graham CA, Spedicati B, Pelliccione G, Gasparini P, Concas MP. Foods 12: 2023 1739	1
Clenching the Strings of Bruxism Etiopathogenesis: Association Analyses on Genetics and Environmental Risk Factors in a Deeply Characterized Italian Cohort. Pecori A, Luppieri V, Santin A, Spedicati B, Zampieri S, Cadenaro M, Girotto G, Concas MP. Biomedicines 12: 2024 304	0