Study
Targeted sequencing of brain expressed miRNA genes
| Study ID | Alternative Stable ID | Type |
|---|---|---|
| EGAS00001001607 | Other |
Study Description
As regulators of gene expression, microRNAs (miRNAs) are likely to play an important role in the development of disease. In this study we present a large-scale strategy to identify miRNAs with a role in the regulation of neuronal processes by screening 289 brain expressed miRNAs. Thereby we found variant rs7861254 located near the MIR204 gene to be significantly associated with schizophrenia. This variant resulted in reduced expression of miR-204 in neuronal-like SH-SY5Y cells.
Study Datasets 4 datasets.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD00001001849 |
The genomic sequence of brain expressed miRNA genes was sequenced in Swedish schizophrenia patients
|
Illumina MiSeq | 186 |
| EGAD00001001850 |
Genomic DNA from Swedish control individuals was pooled. Then the genomic sequence of brain expressed miRNA genes was determined in the pools.
|
Illumina MiSeq | 149 |
| EGAD00001001851 |
The genomic sequence of brain expressed miRNA genes was sequenced in Belgian epilepsy patients.
|
Illumina MiSeq | 163 |
| EGAD00001001852 |
Genomic DNA from Belgian control individuals was pooled. Then the genomic sequence of brain expressed miRNA genes was determined in the pools.
|
Illumina MiSeq | 39 |
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