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BLUEPRINT Epigenetic characterization of megakaryocytes and erythroblasts

Megakaryocytes and erythroblasts derive from the same progenitor cell type but carry out very different functions. In order to understand how the different functional phenotypes arise we have characterised the epigenetic landscape of these cells.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001001871 Illumina HiSeq 2500 20
Publications Citations
Platelet function is modified by common sequence variation in megakaryocyte super enhancers.
Nat Commun 8: 2017 16058
Whole-genome sequencing of patients with rare diseases in a national health system.
Nature 583: 2020 96-102
A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology.
Nat Commun 14: 2023 5023