Study

Korean Young Age Diffuse Gastric Cancers

Study ID Alternative Stable ID Type
EGAS00001001711 Other

Study Description

The incidence of diffuse gastric cancers (DGC) remains steadily high, but relatively small numbers of DGCs have been evaluated with whole exome sequencing (WES). Clinicopathological features of DGC vary according to age, but the molecular basis for these variations is unclear. To identify genomic alteration in this unique subset of gastric cancers, whole exome and SNP6 analyses were performed using frozen cancer tissue. The same analyses were also performed using blood of the same patients.

Study Datasets 3 datasets.

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Dataset ID Description Technology Samples
EGAD00001001984
To identify recurrent somatic alterations in this unique subset of gastric cancers, whole exome and SNP6 analyses were performed using frozen cancer tissue. The somatic mutation analyses were also performed using blood of the same patients.
Illumina HiSeq 2500 160
EGAD00001003953
Fastq files for the whole genome sequencing data (Illumina HiSeq 2500; 32.6-fold) for two diffuse gastric cancers revealing the fusion breakpoints. 2102T: CTNND1-ARHGAP26 gene fusion (g.chr11:57,578,103-g.chr5:142,358,707) 354T: ANXA2-MYO9A gene fusion (g.chr15:60,656,550-g.chr15:72,157,966)
Illumina HiSeq 2500 2
EGAD00010000889
Gencode control samples using SNP6.0
SNP6.0 183

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