Characterization of a human iPSC-derived endocrine pancreas model
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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Directed differentiation of stem cells offers a scalable solution to the need for human cell models recapitulating islet biology and T2D pathogenesis. We profiled mRNA expression at six stages of an induced pluripotent stem cell (iPSC) model of endocrine pancreas development from two donors, and characterized the distinct transcriptomic profiles associated with each stage. Established regulators of endodermal lineage commitment, such as SOX17 (log2 fold change [FC] compared to iPSCs=14.2, ... (Show More)
|Illumina HiSeq 2000||12|