Epigenome and transcriptome profiling of chronic lymphocytic leukemia patients
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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Chronic lymphocytic leukemia (CLL) is characterized by substantial clinical heterogeneity, despite relatively few genetic alterations. To provide a basis for studying epigenome deregulation in CLL, we established genome-wide chromatin accessibility maps for 88 CLL samples from 55 patients using the ATAC-seq assay, and we also performed ChIPmentation and RNA-seq profiling for ten representative samples. Based on the resulting dataset, we devised and applied a bioinformatic method that links ... (Show More)
|Illumina HiSeq 3000;||138|