Study

Genetic subclone heterogeneity of tumor-initiating cells in human colorectal cancer

Study ID Alternative Stable ID Type
EGAS00001001857 Other

Study Description

A subset of tumor-initiating cells (TIC) drives colorectal cancer (CRC) progression in serial mouse xenografts. The TIC compartment itself is heterogeneous and comprises hierarchically organized long-term TIC, tumor transient amplifying cells, and delayed contributing TIC. To address the genomic heterogeneity of the CRC TIC compartment, genome-wide high-coverage whole genome sequencing was performed on patient tumors (n=3), corresponding serially passaged TIC-enriched spheres, and serial xenografts.HIPO P002

Study Datasets 2 datasets.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001002528
WGS from EGAS00001001857
Illumina HiSeq 2000 18
EGAD00001006263
linking 3 samples out of EGAD00001002528 to EGAS0001004517
Illumina HiSeq 2000 3

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