Whole transcriptome and exome sequencing of childhood ALL

Study

Study ID	Alternative Stable ID	Type
EGAS00001001858		Other

Study Description

Gene fusion is a major class of genomic abnormalities in childhood acute lymphoblastic leukemia (ALL) and sentinel chromosomal rearrangements involving EP300 and CREBBP may cause global epigenetic deregulation during leukemogenesis with potentials for therapeutic targeting. This dataset includes whole transcriptome sequencing of 231 children with acute lymphoblastic leukemia from a Singapore-Malaysia frontline clinical treatment protocol.

Study Datasets 2 datasets.

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Dataset ID	Description	Technology	Samples
EGAD00001002151	Whole transcriptome sequencing of 231 children with newly-diagnosed ALL Whole transcriptome sequencing of 231 children with newly-diagnosed ALL	Illumina HiSeq 2000	231
EGAD00001002152	Whole exome sequencing for the matched germline and tumor DNA from 10 ALL cases with ZNF384 rearrangements. Whole exome sequencing for the matched germline and tumor DNA from 10 ALL cases with ZNF384 rearrangements.	Illumina HiSeq 2000	20

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