Study

Whole transcriptome and exome sequencing of childhood ALL

Study ID Alternative Stable ID Type
EGAS00001001858 Other

Study Description

Gene fusion is a major class of genomic abnormalities in childhood acute lymphoblastic leukemia (ALL) and sentinel chromosomal rearrangements involving EP300 and CREBBP may cause global epigenetic deregulation during leukemogenesis with potentials for therapeutic targeting. This dataset includes whole transcriptome sequencing of 231 children with acute lymphoblastic leukemia from a Singapore-Malaysia frontline clinical treatment protocol.

Study Datasets 2 datasets.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001002151
Whole transcriptome sequencing of 231 children with newly-diagnosed ALL
Illumina HiSeq 2000 231
EGAD00001002152
Whole exome sequencing for the matched germline and tumor DNA from 10 ALL cases with ZNF384 rearrangements.
Illumina HiSeq 2000 20

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