Study
CRC Promoter capture Hi-C
Study ID | Alternative Stable ID | Type |
---|---|---|
EGAS00001001946 | Other |
Study Description
Genome organisation determines chromosome interactions between regulatory elements, such as promoters and enhancers, influencing gene expression. Despite the fact that it is possible to assess whether a gene is actively transcribed, it has been challenging to point out the genomic regions that are involved in the regulation of a particular gene. We are interested in better understanding the interactions between promoters and their regulatory elements in colorectal cancer in order to unveil novel non-coding regions which might have a role in tumour development. To do so, we utilise the HiC method complemented with promoter capture in combination with NGS to map promoter interactions in two CRC cell lines, representing two distinct CRC subtypes.
Study Datasets 2 datasets.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
---|---|---|---|
EGAD00001003257 |
Hi-C and promoter capture Hi-C data for HT29 and LoVo.
2 replicates per cell line for the Hi-C.
3 replicates per cell line for the CHi-C.
|
Illumina HiSeq 2000 | 2 |
EGAD00001003258 |
ChIPseq data for H3K4me1 and H3K9me3 in HT29; H3K4me1, H3K27me3, H3K9me3, H3K36me3 in LoVo.
|
Illumina HiSeq 2000 | 2 |
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