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Meta-analysis of Genome-Wide-Association Sudies for plasma Factor XI

Coagulation factor XI (FXI) has become increasingly interesting for its role in pathogenesis of thrombosis. We performed a genome-wide association study (GWAS) for plasma FXI levels, using novel data imputed to the 1000 Genomes reference panel. Individual GWAS analyses, including a total of 16,169 European individuals from the ARIC, GHS, MARTHA and PROCARDIS studies, were meta-analyzed, and results are presented here.

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Dataset ID Description Technology Samples
EGAD00010001141 -
Publications Citations
Genome-wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels.
Hum Mol Genet 26: 2017 637-649
A multitrait genetic study of hemostatic factors and hemorrhagic transformation after stroke treatment.
J Thromb Haemost 22: 2024 936-950