Study
Osteosarcoma X10
Study ID | Alternative Stable ID | Type |
---|---|---|
EGAS00001002167 | Cancer Genomics |
Study Description
This is a continuation of the osteosarcoma work we have undertaken.
Study Datasets 2 datasets.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
---|---|---|---|
EGAD00001006423 |
Leukaemia and related blood cancers occur due to genetic changes that typically accumulate over many years. This study will employ targeted next-generation sequencing to retrace the preclinical evolution of several types of haematological malignancy. Investigating the progression of the earliest pre-malignant ancestral clones promises to offer valuable insights into early leukaemia evolution and therapeutic vulnerabilities of leukaemia stem cells.
|
HiSeq X Ten,Illumina NovaSeq 6000 | 137 |
EGAD00001006859 |
Osteosarcoma, the most common primary malignant tumour of bone, affects children and adults alike. No fundamental biological differences between paediatric and adult osteosarcoma are known. Here, we apply multi-region whole genome sequencing to an index case of a four-year old child whose aggressive tumour harboured high level, focal amplifications of MYC and CCNE1 connected by translocations. We re-analysed copy number readouts of 258 cases of high-grade osteosarcoma from three different ... (Show More)
|
HiSeq X Ten | 8 |
Who archives the data?
