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Integrative analysis of whole genome sequencing, RNA sequencing and methylome array of 20 carcinosarcomas.

Carcinosarcomas of the female genital tract, or GCS, are uncommon but clinically highly aggressive neoplasms with biphasic histology of carcinomatous (C) and sarcomatous (S) elements. These tumors represent a unique model to study the genetic and phenotypic diversity of cancer cells and the link between cellular plasticity and resistance to therapy. The aim of ICGC GCS program is to genomically characterize C and S components of 20 tumors, from endometrium or ovary, through an integrative analysis of whole genome sequencing, RNA sequencing and methylome array.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001003163 Illumina HiSeq 2000 23
EGAD00001003755 Illumina HiSeq 2000 27
EGAD00001003898 Illumina HiSeq 2000 10
EGAD00001009099 Illumina HiSeq 2500 40
EGAD00010001506 Illumina 450k 38
Publications Citations
Dissecting the Origin of Heterogeneity in Uterine and Ovarian Carcinosarcomas.
Cancer Res Commun 3: 2023 830-841
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