WGS of AML during PARPi therapy
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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Analysis of mutational signatures is becoming routine in cancer genomics, with implications for pathogenesis, classification, prognosis, and even treatment decisions. However, the field lacks a consensus on analysis and result interpretation. Using whole-genome sequencing of multiple myeloma (MM), chronic lymphocytic leukemia (CLL) and acute myeloid leukemia, we compare the performance of public signature analysis tools. We describe caveats and pitfalls of de novo signature extraction and ... (Show More)
|HiSeq X Ten||5|