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WGS_of_AML_during_PARPi_therapy

We will require WGS on Illumina X10 machines of three samples, along with storage and computational power to perform the relevant analysis.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001005028 HiSeq X Ten 5
Publications Citations
A practical guide for mutational signature analysis in hematological malignancies.
Nat Commun 10: 2019 2969
115
mmsig: a fitting approach to accurately identify somatic mutational signatures in hematological malignancies.
Commun Biol 4: 2021 424
20
The evolution of hematopoietic cells under cancer therapy.
Nat Commun 12: 2021 4803
30
Copy number signatures predict chromothripsis and clinical outcomes in newly diagnosed multiple myeloma.
Nat Commun 12: 2021 5172
21
Tracking the evolution of therapy-related myeloid neoplasms using chemotherapy signatures.
Blood 141: 2023 2359-2371
21