Multi-region sequencing of metastatic colorectal cancer

In order to reconstruct the evolutionary history of metastatic colorectal cancer, we performed whole-exome sequencing of 10 metastatic colorectal cancer patients for whom the primary tumor and matched distant metastases to the brain (n=10), liver (n=1), lung (n=1), as well as lymph node metastases (n=4) were available. For 6 of the 10 patients, multiple regions (n=2-5) of the primary tumor and distant metastases were sequenced.

• Type: Other
• Archive: European Genome-phenome Archive (EGA)