Study

Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population

Study ID Alternative Stable ID Type
EGAS00001002641 Other

Study Description

We recently showed that a common genetic variant leads to a remarkably increased risk of type 2 diabetes (T2D) in the small and historically isolated Greenlandic population. Motivated by this, we aimed at investigating the genetic determinants for glycated hemoglobin (HbA1C). We found no novel associations but saw that for 10 out of 15 known HbA1C loci that the effects in Greenlandic Inuit were similar to previously reported. One locus, ANK1, showed a significant ancestral population specific effect. Our results shed light on the genetics effects across ethnicites.

Study Datasets 2 datasets.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00010001427
Cardio-Metabochip genotypes for B99 cohort
Illumina 1336
EGAD00010001428
Cardio-Metabochip genotypes for IHIT cohort
Illumina 2791

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