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H3Africa - Collaborative African Genomics Network

Genomic studies have become one of the potential tools that could aid in the understanding of disease. HIV disease progression and active TB infection have been studied using these genomic methods to interrogate host factors associated with these diseases and their progression. Prior work has focused on adult populations and limited African cohorts. The Collaborative African Genomics Network aims to fill this gap by conducting HIV and TB disease mapping studies in African children to understand how genetic variation impacts disease progression through the use of genomic technologies.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001006224 Illumina HiSeq 2500 314
Publications Citations
Unmapped exome reads implicate a role for Anelloviridae in childhood HIV-1 long-term non-progression.
NPJ Genom Med 6: 2021 24
Polygenic risk scores for disease risk prediction in Africa: current challenges and future directions.
Genome Med 15: 2023 87