Study

Detection of clinically relevant genetic and transcriptomic landscape in DLBCL uniformly treated by R-CHOP

Study ID Alternative Stable ID Type
EGAS00001002657 Other

Study Description

Recent studies using next-generation sequencing strategies have described the landscape of genetic alterations in diffuse large B-cell lymphoma (DLBCL). However, little is known about the clinical relevance of recurrent mutations and copy number alterations and their transcriptional footprints. This study examines the frequency, interaction and clinical impact of recurrent genetic aberrations in DLBCL using high-resolution technologies in a large population-based cohort.

Study Datasets 2 datasets.

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Dataset ID Description Technology Samples
EGAD00001003783
Recent studies using next-generation sequencing strategies have described the landscape of genetic alterations in diffuse large B-cell lymphoma (DLBCL). However, little is known about the clinical relevance of recurrent mutations and copy number alterations and their transcriptional footprints. This study examines the frequency, interaction and clinical impact of recurrent genetic aberrations in DLBCL using high-resolution technologies in a large population-based cohort.
Illumina HiSeq 2000,Illumina HiSeq 2500 376
EGAD00010001980
Microarray data for 341 DLBCL patients
Affymetrix Human Gene 2.0 ST Array 341

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