Study
Genomic analysis Nasopharyngeal cancer through whole exome sequencing and whole genomic sequencing.
Study ID | Alternative Stable ID | Type |
---|---|---|
EGAS00001002788 | Other |
Study Description
Nasopharyngeal carcinoma (NPC) is a squamous-cell carcinoma and has remarkable ethnic and geographic distribution, with a high prevalence in southern China, southeast Asia, northern Africa and Alaska. Although there are previous studies implicated NF-κB pathway play an important role in NPC. Newer research also found several important cellular processes and pathways in NPC, including chromatin modification, ERBB-PI3K signaling and autophagy machinery. Put these studies together, although, NPC is still poorly understood at the genetic level. Here we determined the mutational landscape of 553 cases with NPC using whole-genomic and whole-exome sequencing. These approaches revealed a distinct mutational signature and significantly mutated genes.
Study Datasets 1 dataset.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
---|---|---|---|
EGAD00001004008 |
This dataset include NPC blood tumor pair sequencing bam file, include 21 pairs, 42 bam files
|
Illumina HiSeq 2000 | 42 |
Who archives the data?
