Somatic mutation and clonal evolution normal breast tissue TGS
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
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Cancer is a genetic disease caused by an accumulation of mutations, however many of these mutations have been identified in pathologically normal tissue. We aim to use laser-capture microscopy (LCM) to sample individual clones from breast tissue to identify whether cancer-associated mutations appear in this normal tissue, assess the mutational burden present, and identify the mutational processes causing these mutations. We will sample from a wide age range of individuals (<20 to >70 ... (Show More)
|Illumina HiSeq 4000||689|