Genome-wide discovery of somatic coding and regulatory variants in Diffuse Large B-cell Lymphoma
|Study ID||Alternative Stable ID||Type|
Study Datasets 2 datasets.
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Recent studies using next-generation sequencing strategies have described the landscape of genetic alterations in diffuse large B-cell lymphoma (DLBCL). However, little is known about the clinical relevance of recurrent mutations and copy number alterations and their transcriptional footprints. This study examines the frequency, interaction and clinical impact of recurrent genetic aberrations in DLBCL using high-resolution technologies in a large population-based cohort.
|Illumina HiSeq 2000,Illumina HiSeq 2500||376|
146 DNA samples obtained from 73 DLBCL patients (matching tumor and normal) were sequenced with PCR free 1.0 genome shotgun sequencing. All files are in bam format.