Age-related remodeling of apparently normal esophageal epithelia by common cancer drivers

Study ID Alternative Stable ID Type
EGAS00001003008 Other

Study Description

Driver mutated clones multi-focally emerged from early adulthood and over years, increase their number and size, ultimately remodeling the entire esophageal epithelia in extreme elderly. Our results suggest that clonal expansion in esophageal epithelia is an inevitable consequence of normal aging, differentially impacting the development of cancer depending on mutation type and exposure to drinking and smoking.

Study Datasets 1 dataset.

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Dataset ID Description Technology Samples
whole exome sequencing data
Illumina HiSeq 2000 523

Who archives the data?

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