Need Help?

Histone acetylome-wide association study on tuberculosis infection

Epigenetic mechanisms are thought to play an important role in the pathogenesis of infectious diseases. Here, we describe the first histone acetylome-wide association study (HAWAS) of an infectious disease, based on genome-wide H3K27 acetylation profiling of peripheral granulocytes and monocytes from subjects with active Mycobacterium tuberculosis (Mtb) infection and healthy controls (135 ChIP-seq datasets).

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001004206 Illumina HiSeq 2000 161
Publications Citations
Histone acetylome-wide associations in immune cells from individuals with active Mycobacterium tuberculosis infection.
Nat Microbiol 7: 2022 312-326