Histone acetylome-wide association study on tuberculosis infection

Study

Study ID	Alternative Stable ID	Type
EGAS00001003118		Other

Study Description

Epigenetic mechanisms are thought to play an important role in the pathogenesis of infectious diseases. Here, we describe the first histone acetylome-wide association study (HAWAS) of an infectious disease, based on genome-wide H3K27 acetylation profiling of peripheral granulocytes and monocytes from subjects with active Mycobacterium tuberculosis (Mtb) infection and healthy controls (135 ChIP-seq datasets).

Study Datasets 1 dataset.

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Dataset ID	Description	Technology	Samples
EGAD00001004206	This dataset contains 135 H3K27ac ChiP-seq experiments. Monocytes and granulocytes from TB and non-TB samples were obtained, ChIP-seq was performed, and the reads were aligned to hg19. This dataset contains 135 H3K27ac ChiP-seq experiments. Monocytes and granulocytes from TB and non-TB samples were obtained, ChIP-seq was performed, and the reads were aligned to hg19.	Illumina HiSeq 2000	161

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