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iNeuron_ChIPseq

Characterisation of the chromatin status of induced neurons (iNeurons) generated by overexpression of the Ngn2 transcription factor transgenically in BOB iPS cells at the excitatory cortical neuron and iPSC stages. The aim is to understand the differentiation trajectory and characterise the chromatin status so that we can understand the impact of chromatin on gene expression during this transition. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001010050 Illumina HiSeq 4000 Illumina NovaSeq 6000 38
Publications Citations
Massively parallel characterization of CRISPR activator efficacy in human induced pluripotent stem cells and neurons.
Mol Cell 83: 2023 1125-1139.e8
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