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Profiling of Peritoneal Metastases from Gastric Adenocarcinoma Identified Molecular Subtypes

Peritoneal carcinomatosis (PC) occurs frequently in gastric adenocarcinoma (GAC) patients and confers poor prognosis. Multiplex profiling of primary GACs has been insightful but the underpinnings of PC’s development/progression remain largely unknown. Here we characterized exome/transcriptome/immune landscapes of PC cells from 43 patients.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001004364 Illumina HiSeq 4000 49
EGAD00001004365 Illumina HiSeq 4000 39
Publications Citations
Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response.
Gut 69: 2020 18-31
YAP1 mediates gastric adenocarcinoma peritoneal metastases that are attenuated by YAP1 inhibition.
Gut 70: 2021 55-66
Proteogenomic landscape of gastric adenocarcinoma peritoneal metastases.
iScience 26: 2023 106913