Study

46 CLL Whole Genome Sequencing Study

Study ID Alternative Stable ID Type
EGAS00001003254 Other

Study Description

Chronic lymphocytic leukaemia (CLL) consists of two biologically and clinically distinct subtypes defined by the abundance of somatic hypermutation (SHM) affecting the Ig variable heavy-chain locus (IgHV). The molecular mechanisms underlying these subtypes are incompletely understood. Here, we present a comprehensive whole-genome sequencing analysis of somatically acquired genetic events from 46 CLL patients, including a systematic comparison of coding and non-coding single nucleotide variants, copy number variants and structural variants, regions of kataegis and mutation signatures between IgHVmut and IgHVunmut subtypes.

Study Datasets 1 dataset.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001004384
Whole Genome Sequencing of 44 patients with Chronic Lymphocytic Leukemia. This dataset comprises 44 .bam files aligned to the hg19 build of the human genome from sequencing reads generated on an Illumina HiSeq instrument.
Illumina HiSeq 2500 44

Who archives the data?

There are no publications available