Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
The goal of the sequencing study was to determine the neoantigen profile of melanoma patients. We performed whole exome sequening of the tumor and respective patien matched PBMC samples (2x50nt) and RNA-sqeuencing of the tumor samples. The was analyzed for somatic point mutaions, using the RNA-Seq data to determine mutation expression. This study contains the exome seq data.
- Type: Other
- Archiver: EGA European Genome-Phenome Archive
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
|EGAD00001004455||Illumina HiSeq 2500||72|
Accurate detection of tumor-specific gene fusions reveals strongly immunogenic personal neo-antigens.
Nat Biotechnol 40: 2022 1276-1284