MutWP5 CRUK Mutographs of Cancer Breast BRCA Carriers Exome
|Study ID||Alternative Stable ID||Type|
Study Datasets 1 dataset.
Sequencing of LCM-derived microbiopsies from 20 women who underwent risk-reducing reduction mastectomies due to germline BRCA1/2. Goal to assess the mutational burden, spectrum, and clonal dynamics within the tissue. Exome data will be used as a driver and clonality screen, highly clonal or driver-containing samples will subsequently be sent for whole-genome sequencing. Results from this portion of the study will be compared to women who had cosmetic breast reduction surgeries and those with ... (Show More)
|Illumina HiSeq 4000||8|