Study

RNAseq data from human colon organoid infected by KP

Study ID Alternative Stable ID Type
EGAS00001003332 Other

Study Description

The aim of this study is to identify the specific bacteria that are responsible for pathological bacterial translocation and subsequent Th17 priming in the liver in primary sclerosing cholangitis (PSC). To clarify the mechanism of how microbiota interacts with the intestinal epithelial barrier, monolayered human intestinal organoids were cultured with the specific bacteria. Gene expression analysis using RNA sequencing in epithelial cells cultured with Klebsiella pneumoniae derived from a PSC patient (KP-P1) or commercially obtained Klebsiella pneumoniae strain (KP JCM1662) was performed in this study.

Study Datasets 1 dataset.

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Dataset ID Description Technology Samples
EGAD00001004465
Gene expression comparison between human colonic epithelial cells cultured with Klebsiella pneumoniae (KP) derived from PSC patients versus KP JCM1662.
Illumina HiSeq 2500 4

Who archives the data?

There are no publications available