Study
Evaluation of commercial Guardant360 ctDNA test in metastatic prostate cancer
Study ID | Alternative Stable ID | Type |
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EGAS00001003352 | Other |
Study Description
Circulating tumor DNA (ctDNA) sequencing provides a minimally-invasive method for tumor molecular stratification. We compared the commercial Guardant360 ctDNA test to an academic sequencing approach for profiling of metastatic prostate cancer. Plasma cell-free DNA (cfDNA) from 24 patients was sequenced with a validated, prostate cancer specific targeted research panel, and sent for simultaneous Guardant360 analysis.
Study Datasets 1 dataset.
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Dataset ID | Description | Technology | Samples |
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EGAD00001004486 |
This dataset consists of aligned DNA sequencing data in BAM file format from cell-free DNA and white blood cells from 24 men with metastatic prostate cancer. One cell-free DNA sample and one white blood cell sample is available for each patient, resulting in 48 total BAM files in this dataset. The sequencing was performed using a hybrid capture-based targeted panel of 73 prostate cancer driver genes.
|
Illumina HiSeq 2500 | 48 |
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