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Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases

Through whole-genome methylation analysis of plasma samples from patients with nasopharyngeal carcinoma (NPC), EBV-associated lymphoma and infectious mononucleosis, we demonstrate that EBV DNA methylation profiles exhibit a disease-associated pattern. Such observation implies significant potentials in the development of methylation analysis of plasma EBV DNA for NPC diagnostics.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001005088 NextSeq 500 236
Publications Citations
Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseases.
Nat Commun 10: 2019 3256
31
Epigenetic analysis of cell-free DNA by fragmentomic profiling.
Proc Natl Acad Sci U S A 119: 2022 e2209852119
16