We isolated T cells and monocotyes from healthy platelet donors and cultured them in resting and stimulated conditions with addition of a range of cytokines. We performed ATAC sequencing to assess the chromatin accessability in different cytokines treated cells. These cellular profiles were used to map risk variants to the cytokine-induced cell states relevant for autoimmune diseases.
- Type: Epigenetics
- Archiver: EGA European Genome-Phenome Archive
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
|EGAD00001004831||Illumina HiSeq 2500 Illumina MiSeq||183|
Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases.
Nat Genet 51: 2019 1486-1493