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We isolated T cells and monocotyes from healthy platelet donors and cultured them in resting and stimulated conditions with addition of a range of cytokines. We performed ATAC sequencing to assess the chromatin accessability in different cytokines treated cells. These cellular profiles were used to map risk variants to the cytokine-induced cell states relevant for autoimmune diseases.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001004831 Illumina HiSeq 2500 Illumina MiSeq 183
Publications Citations
Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases.
Nat Genet 51: 2019 1486-1493