Understanding Self Organising Capacity of Stem Cells during Implantation and Early Post implantation Development in vitro and in vivo Implications for Human Development
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The aim of this project is to differentiate human embryonic stem cells to an extra-embryonic fate, specifically the hypoblast. This is of uttermost importance given the current lack of human hypoblast stem cells. We hypothesized that the pluripotent characteristics of the starting human embryonic stem cell population may dictate the competency for extra-embryonic cell fate specification. Based on this hypothesis and using human embryonic stem cells maintained in different naïve-like culture ... (Show More)
|Illumina HiSeq 4000||7|