Genetic and expression landscape of Waldenstrom macroglobulinemia

Exome analyses for the identification of somatic mutation in Waldenstrom macroglobulinemia by comparison of tumor and CD3+(germ line control) population in 16 patients. transcription profiling of a series of Waldenstrom macroglobulinemia samples

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

4 Datasets

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Dataset ID	Description	Technology	Samples
EGAD00001005322	DNA extracted from sorted CD19+ tumor cells (18 samples - 16 patients) was used for exome capture with the SureSelect All Exon Kit following the standard protocols. Paired-end sequencing (2 x 100 bp) was performed using HiSeq2000 sequencing instruments. The files are in FASTQ format.	Illumina HiSeq 2000	18
EGAD00001005323	DNA extracted from sorted CD3+ cells (16 patients) was used for exome capture with the SureSelect All Exon Kit following the standard protocols. Paired-end sequencing (2 x 100 bp) was performed using HiSeq2000 sequencing instruments.The files are in FASTQ format.	Illumina HiSeq 2000	16
EGAD00001005324	RNA was extracted from flow-sorted CD19+. RNA-Seq was performed on 32 samples of 30 patients (2 replicates per samples). RNA-Seq libraries were subjected to non-stranded paired-end (2 x 75 bp) sequencing on HiSeq 2500 (Illumina). The files are in FASTQ format.	Illumina HiSeq 2500	64
EGAD00010001861	Genome-wide DNA methylation profiling of Waldenstrom's macroglobulinemia (WM) patient samples	Infinium MethylationEPIC Kit (Illumina)	48