Comprehensive molecular profiling of high-grade serous ovarian cancer
The diversity and heterogeneity within high-grade serous ovarian cancer (HGSC) is not well understood. Here, we performed comprehensive molecular analysis, including high-pass whole genome sequencing, targeted deep sequencing, RNA sequencing, reverse phase protein arrays and immune assessment, on primary and metastatic sites from highly clinically annotated HGSC samples. Samples were obtained pre-treatment based on a laparoscopic triage algorithm from patients who underwent R0 tumor debulking, or received neoadjuvant chemotherapy (NACT) with excellent or poor response.
- Type: Other
- Archiver: EGA European Genome-Phenome Archive
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
|EGAD00001005238||Illumina HiSeq 2000||74|
|EGAD00001005239||Illumina HiSeq 2000||75|
|EGAD00001005240||HiSeq X Ten||103|
Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer.
Cell Rep 31: 2020 107502
Spatially resolved transcriptomics of high-grade serous ovarian carcinoma.
iScience 25: 2022 103923