Lothian Birth Cohort 1936 whole genome sequencing study
1075 members of the Lothian Birth Cohort 1936 (LBC1936) were sequenced using the Illumina HiSeq X platform. The LBC1936 are a relatively healthy cohort of 1091 individuals who underwent cognitive and medical testing at a mean age of 69.5 (SD=0.8) years. They have since undergone four further waves of testing, approximately three years apart.
- Type: Other
- Archiver: European Genome-Phenome Archive (EGA)
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD00001005478 | Illumina HiSeq X Ten | 1068 | |
| EGAD00001006414 | Illumina HiSeq X Ten | 1075 | |
| EGAD00001008774 | Illumina HiSeq X Ten | 1075 |
| Publications | Citations |
|---|---|
|
Increased ultra-rare variant load in an isolated Scottish population impacts exonic and regulatory regions.
PLoS Genet 15: 2019 e1008480 |
13 |
|
Using regulatory variants to detect gene-gene interactions identifies networks of genes linked to cell immortalisation.
Nat Commun 11: 2020 343 |
5 |
|
Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936.
Stem Cell Res 46: 2020 101851 |
11 |
|
Rare genetic variants underlie outlying levels of DNA methylation and gene-expression.
Hum Mol Genet 32: 2023 1912-1921 |
1 |