Gene epression regulation in cytokine induced immune cell states
|Study ID||Alternative Stable ID||Type|
|EGAS00001003823||Gene Regulation Study|
Study Datasets 1 dataset.
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Cytokines affect T cell responses by polarising them to different phenotypes. We isolated T cells from healthy platelet donors and cultured them in resting and stimulated conditions, as well as in the presence of Th1, Th2, Th17 and iTreg cocktail. In addition, T cells were stimulated in the presence of IL-10, IL-21, IL-27, IFNb and TNFa. We performed bulk RNA sequencing to assess impact of different disease-relevant cytokines upon T cell response.
|Illumina HiSeq 2500||141|