Bottleneck_Sequencing_Of_Human_Tissue__Wgs_
Bottleneck sequencing of human tissue including neurons, cord blood, sperm This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
- Type: Cancer Genomics
- Archiver: European Genome-Phenome Archive (EGA)
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
Dataset ID | Description | Technology | Samples |
---|---|---|---|
EGAD00001006459 | HiSeq X Ten Illumina HiSeq 2500 Illumina HiSeq 4000 Illumina NovaSeq 6000 | 192 | |
EGAD00001007958 | Illumina NovaSeq 6000 | 210 | |
EGAD00001007997 | Illumina NovaSeq 6000 | 31 |
Publications | Citations |
---|---|
Increased somatic mutation burdens in normal human cells due to defective DNA polymerases.
Nat Genet 53: 2021 1434-1442 |
68 |
Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells.
Nat Commun 13: 2022 3949 |
26 |