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End structure of DNA in plasma: detection, characterizationand diagnostic applications

The physical properties of cell-free DNA fragments in plasma, such as fragment sizes and ends, have attracted much recent interest, leading to the emerging field of fragmentomics. This study attempted to further characterize the end structure of plasma DNA.

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID Description Technology Samples
EGAD00001006054 Illumina HiSeq 4000 29
Publications Citations
Detection and characterization of jagged ends of double-stranded DNA in plasma.
Genome Res 30: 2020 1144-1153
35
Fragmentation landscape of cell-free DNA revealed by deconvolutional analysis of end motifs.
Proc Natl Acad Sci U S A 120: 2023 e2220982120
7