Chracterising cellur pathways underlying CD3 CD28 activation of human CD4 cells
|Study ID||Alternative Stable ID||Type|
|EGAS00001004147||Gene Regulation Study|
Study Datasets 1 dataset.
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We devised an approach to disentangle the TCR and CD28 pathways upon stimulation in naive and memory primary human CD4+ T cells (Tcons) in response to defined stimulatory signals. Sorted Tcons were activated using a titration of anti-CD3 and anti-CD28 in combination as well as individually. As a control we cultured cells in the same conditions but without the stimuli. In total, we defined seven conditions from four individuals for sequencing. This data is part of a pre-publication release. For ... (Show More)
|Illumina HiSeq 2500||30|