Study
Genomic and epigenomic insights into the origin, pathogenesis and clinical behavior of mantle cell lymphoma subtypes
| Study ID | Alternative Stable ID | Type |
|---|---|---|
| EGAS00001004165 | Other |
Study Description
Mantle Cell Lymphoma can be subdivided into conventional (cMCL) and leukemic non-nodal MCL (nnMCL), which differ in the cell of origin, gene expression, biological characteristics and clinical evolution. Using genomic, epigenomic and transcriptomic data we identified common and particular alterations in the two subtypes, either point mutations, copy number alterations or structural variants some of them with prognostic impact.
Study Datasets 4 datasets.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD00001006025 |
We have performed a comprehensive and integrative genomic
study of mantle cell lymphoma (MCL) to elucidate the features that may determine the
different clinical and biological behavior of the two molecular subtypes of this
lymphoma, conventional (cMCL) and leukemic non-nodal MCL (nnMCL). This data integrated with epigenomics and transcriptomics has allowed to uncover novel molecular mechanisms in the origin and development of these tumors and provide relevant information to stratify patients ... (Show More)
|
Illumina MiSeq | 114 |
| EGAD00010001841 |
Copy Number Alterations arrays from 153 samples performed by Affymetrix 6.0 and Oncoscan CNV platforms
|
Affymetrix 6.0; Cytoscan | 153 |
| EGAD00010001842 |
Gene Expression Profiling from 44 Mantle Cell Lymphoma cases
|
Human Genome U219 array plate | 44 |
| EGAD00010001877 |
DNA methylation profiling from 70 Mantle Cell Lymphoma cases
|
Infinium MethylationEPIC BeadChip | 70 |
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