The role of the mammalian SWI/SNF chromatin remodeling complex in neuroendocrine prostate cancer
|Study ID||Alternative Stable ID||Type|
We sought to determine the effects of SMARCA4 and SMARCA2 depletion in prostate cancer cell lines. We performed siRNA-mediated knock-down of SMARCA4 and SMARCA2 in an androgen-sensitive (LNCaP) cell line and in a castration-resistant prostate cancer (CRPC)-adenocarcinoma cell line (22Rv1) and compared global transcriptional alterations using RNA-seq.
Study Datasets 2 datasets.
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RNA-seq of SMARCA2/4 knock-down prostate cancer cell lines (LNCaP and 22Rv1, 15 samples altogether). Dataset contains BAM files from RNA-seq performed using Illumina HiSeq 2500.
|Illumina HiSeq 2500||15|
RNA-seq of Bone Metastasis from breast and prostate cancer (4 breast and 5 prostate samples). Dataset contains BAM files from RNA-seq performed using Illumina HiSeq 2500.
|Illumina HiSeq 2500,Illumina NovaSeq 6000,Ion Torrent S5 XL||288|
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