Comprehensive molecular characterization of brainstem glioma

Brainstem gliomas are the most devastating and lethal tumors. Survival rates are among the lowest in all cancers and options for intervention are likewise low. Due to anatomical delicacy of these areas, resection of tumors is particularly difficult and attempted resections have high perioperative mortality rates. Genomic and epigenetic studies often provide a gateway to functional studies of specific classifications of tumors that can lead to major breakthroughs in diagnosis and treatment options.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

3 Datasets 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001006093	Targeted panel sequencin on Illumina HiSeq X Ten of brainstem glioma primary tumor and blood samples	HiSeq X Ten	42
EGAD00001006094	RNAseq on Illumina HiSeq X Ten of brainstem glioma primary tumor sample	HiSeq X Ten	75
EGAD00010001859	Epigenome of brainstem gliomas	Illumina Methylation Array	123

Publications	Citations
The integrated genomic and epigenomic landscape of brainstem glioma. Chen LH, Pan C, Diplas BH, Xu C, Hansen LJ, Wu Y, Chen X, Geng Y, Sun T, Sun Y, Zhang P, Wu Z, Zhang J, Li D, Zhang Y, Wu W, Wang Y, Li G, Yang J, Wang X, Xu C, Wang S, Waitkus MS, He Y, McLendon RE, Ashley DM, Yan H, Zhang L. Nat Commun 11: 2020 3077	34