Study
An epigenetic single-cell atlas of IDH-mutant glioma reveals the role of ATRX in shaping tumor composition
| Study ID | Alternative Stable ID | Type |
|---|---|---|
| EGAS00001004523 | Other |
Study Description
Recent single-cell RNA-sequencing studies have identified a hierarchy of cell types that is common to all isocitrate dehydrogenase (IDH) -mutant gliomas. This finding is somewhat paradoxical since the genetic differences between IDH-mutant astrocytomas and IDH-mutant oligodendrogliomas are prognostic, predictive of therapeutic response, and correlated with differences in immune infiltrates. To integrate these disparate findings, we constructed a single-cell atlas of 22 human IDH-mutant primary untreated grade-II/III gliomas.
Study Datasets 21 datasets.
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
| Dataset ID | Description | Technology | Samples |
|---|---|---|---|
| EGAD00001006311 |
SF11940 snATAC Sequencing.Anaplastic Astrocytoma, IDH-mutant.
Tumor location: Left Frontal. Age: 29. Sex: Male .
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001006312 |
SF10679 snATAC Seq. Oligodendroglioma, Anaplastic (WHO gr. 3). Tumor Location: Frontal Age: 43. Sex: Male.
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001006313 |
SF11310 Oligodendroglioma, IDH-mutant.Tumor Location: Frontal. Age:22. Sex: Female
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001006314 |
SF10320 Unknown.
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001006315 |
SF12374 snATAC Oligodendroglioma. Tumor Location: Right frontal. Age: 33. Sex: Male.
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001006316 |
SF10619 snATAC Oligodendroglioma (WHO gr. 2).Tumor Location: Parietal. Age: 52. Sex: Male
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001006317 |
SF4007 snATAC Seq. Oligodendroglioma (WHO gr. 2) Tumor Location: Left frontotemporal. Age:33. Sex: Female.
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001006318 |
Astrocytoma (WHO gr. 2)
|
Illumina NovaSeq 6000 | 2 |
| EGAD00001006319 |
SF10207 snATAC Seq. Oligodendroglioma, Anaplastic (WHO gr. 3). Tumor Location:Frontal. Age:43. Sex: Male
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001008297 |
Oligodendroglioma (WHO gr. 2)
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001008298 |
Oligodendroglioma, Anaplastic (WHO gr. 3
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001008299 |
Oligodendroglioma (WHO gr. 2
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001008300 |
Oligodendroglioma (WHO gr. 2
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001008301 |
Oligodendroglioma, IDH-mutant, 1p19q codeleted
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001008302 |
Oligodendroglioma, Anaplastic (WHO gr. 3
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001008303 |
Unknown
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001008304 |
Anaplastic Astrocytoma, IDH-mutant
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001008305 |
Astrocytoma (WHO gr. 2)
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001008306 |
Oligodendroglioma (WHO gr. 2)
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001008307 |
Astrocytoma, Anaplastic (WHO gr. 3
|
Illumina NovaSeq 6000 | 1 |
| EGAD00001008308 |
Oligodendroglioma (WHO gr. 2)
|
Illumina NovaSeq 6000 | 1 |
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