Exome sequencing of DNA from pituitary neuroendocrine tumor (PitNET) and germline DNA from the same patient

The goal of the project is to study tumor - normal DNA pairs from the PitNET patients. Total of 15 PitNET patients were recruited for the study to investigate sometic changes in the tumor compared to normal tissue. Illumina technology were used for sequencing and two data analysis pipelines employed for data analysis. Recurrent somatic variations were investigated and genomic disruption analysis from exome sequencing data attempted.

Type: Other
Archiver: European Genome-Phenome Archive (EGA)

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001006390	PitNET white blood cell DNA - tumor DNA exome sequencing samples with Illumina exome sequencing. Fifteen patients and total of 30 exomes.	NextSeq 500	30

Publications	Citations
Whole exome sequencing reveals novel risk genes of pituitary neuroendocrine tumors. Peculis R, Rovite V, Megnis K, Balcere I, Breiksa A, Nazarovs J, Stukens J, Konrade I, Sokolovska J, Pirags V, Klovins J. PLoS One 17: 2022 e0265306	1