UROMOL 2020 - RNA-seq data
The molecular landscape in non-muscle-invasive bladder cancer (NMIBC) is characterized by large biological heterogeneity with variable clinical outcomes. Here, we performed a large integrative multi-omics analysis of patients diagnosed with NMIBC (n=834). Transcriptomic analysis identifies four classes (1, 2a, 2b and 3) reflecting tumor biology and disease aggressiveness. Both transcriptome-based subtyping and the level of chromosomal instability provide independent prognostic value beyond established prognostic clinicopathological parameters.
- Type: Other
- Archiver: EGA European Genome-Phenome Archive
Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data
|EGAD00001006656||Illumina HiSeq 2000 Illumina MiSeq Illumina NovaSeq 6000 NextSeq 550||535|
An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer.
Nat Commun 12: 2021 2301
A transcriptional network of cell cycle dysregulation in noninvasive papillary urothelial carcinoma.
Sci Rep 12: 2022 16538