Low-C on Human CB-derived LT-HSC and ST-HSC

Study ID Alternative Stable ID Type
EGAS00001004744 Epigenetics

Study Description

Study Datasets 1 dataset.

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Dataset ID Description Technology Samples
To elucidate the epigenetic changes which occur when human long-term hematopoietic stem cells (LT-HSC) become activated we performed Bulk ATAC-Seq on 13 sorted bulk hematopoietic populations from cord bloodas well as single-cell ATAC-Seq upon CD34+CD38-CD45RA- cells enriched for HSC as well as CD34+/CD38+ progenitor cells both from cord blood. These studies revealed gains of chromatin accessibility around CTCF binding sites during HSPC activation, as such we additionally performed Low-C to ... (Show More)
Illumina HiSeq 2000,Illumina HiSeq 2500,NextSeq 500,unspecified 62

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